Cocaine Poisoning

Basics

Description

  • Sympathomimetic
  • Inhibits neurotransmitter reuptake at the nerve terminal
  • Metabolism:
    • Hepatic degradation
    • Nonenzymatic hydrolysis
    • Cholinesterase metabolism

Etiology

  • IV, nasal, oral administration of cocaine
  • Oral ingestion:
    • Body stuffers:
      • Ingest hastily wrapped packets in attempt to evade police
    • Body packers:
      • Ingest cocaine packets to smuggle the drug using couriers’ oral, rectal, and vaginal cavities
      • Cocaine is wrapped carefully in packets containing large amounts of drug

There's more to see -- the rest of this topic is available only to subscribers.

© 2000–2025 Unbound Medicine, Inc. All rights reserved