Lyme Disease
Basics
Basics
Basics
Description
Description
- Most common tick-borne illness in North America
- Endemic in Northeast, Upper Midwest, and northwestern California
Etiology
Etiology
- Peak April–November; 80–90% in summer months
- Spirochete Borrelia burgdorferi introduced by Ixodes tick:
- Ixodes scapularis(deer tick) most common
- Same tick that transmits anaplasmosis, babesiosis
- Pathogenesis—combination of:
- Organism-induced local inflammation
- Cytokine release
- Autoimmunity
- No person-to-person transmission
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